An official Web site of The us govt. This is how you recognize we are Formal. dot gov icon Nonabsorbed ursodiol passes to the colon exactly where it is generally seven-dehydroxylated to lithocholic acid. Some ursodiol is epimerized to chenodiol (CDCA) via a seven-oxo intermediate. Chenodiol also undergoes 7-dehydroxylation https://www.youtube.com/watch?v=A07qHOeWON8