An extensive literature critique of research in between 1995 and 2018 was carried out using the electronic databases PubMed and EBSCO Host. Searches had been done utilizing the following terms: total knee arthroplasty (TKA); cyclooxygenase-2 inhibitors; bracing; Bodily therapy; fat reduction; knee; treatment; therapeutics; OA; intra-articular injection; hyaluronic acid; corticosteroid; https://www.theorthopaedicandpainpractice.com/non-surgical-treatments-for-knee-joint-pain/