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DNA ligases seal five′-PO4 and three′-OH polynucleotide ends via a few nucleotidyl transfer measures involving ligase-adenylate and DNA-adenylate intermediates. DNA ligases are crucial guardians of genomic integrity, and ligase dysfunction underlies human genetic illness syndromes. Crystal structures of DNA ligases certain to nucleotide and nucleic acid substrates have illuminated https://deanjqsxa.ka-blogs.com/81370449/the-best-side-of-official-site-https-ligaz-bet

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