In older individuals, This can be very important to be aware of as polypharmacy is widespread and can potentiate the potential risk of DDIs and ADRs. Consequently, concurrent ingestion of CYP2D6 inhibitors or inducers could potentiate or block tramadol conversion into ODT and This may enhance or decrease efficacy/ADRs https://algirdaso627hxo2.wikiinside.com/user